this post was submitted on 10 Oct 2023
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I have wondered many times how a human would fare if the kidneys dumped urine into the start of the large intestines somewhere about the appendix instead of into a bladder to be sprayed out. I'm assuming water would be reabsorbed and slower to process out, primarily through sweat and evaporation from the lungs, and maybe diarrhea, though it may be that other waste products, such as salts or ureas may be absorbed into the large intestines instead of being ejected, though I have no idea if it would, or if it would be ejected as intended. Do we have any biologists here that could give insight on if combining both waste paths into one would be advisable?

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[–] readyno@lemmy.world 57 points 11 months ago (4 children)

Am doctor, you are essentially asking about a fistula (abnormal communication) that would allow urine and bowel to mix. This would allow for communication of gut bacteria to then invade the urinary system which would then easily cause a kidney infection which would then seed the blood resulting in bacteremia. Bacteremia is bad, like you die from infection unless you are on IV antibiotics and get the source under control bad. As an example, colovesicular fistula is a communication between the colon and bladder which often results in bad infections and needs to be surgically repaired. Hope this helps.

[–] Delphia@lemmy.world 20 points 11 months ago (3 children)

Ok but why cant I have a secondary urethra grafted in that runs in my leg down to a nice discreet exit on my ankle so I can take a sneaky wee when Im out and about.

[–] finthechat@kbin.social 10 points 11 months ago (2 children)

You could just tape a garden hose to your dick and run it down a pant leg. Man, I should patent this idea....

[–] roguetrick@kbin.social 8 points 11 months ago

That's called a condom catheter. Don't hook it up to suction.

[–] Resistentialism@feddit.uk 1 points 11 months ago

I can't. Hose widths are too big.

[–] Mac@mander.xyz 2 points 11 months ago

Look up an endurance racing catheter.

[–] Thurkeau@lemmy.world 2 points 11 months ago (2 children)

Then you'd be right back where you started for my purposes, still losing moisture unnecessarily.

[–] Delphia@lemmy.world 8 points 11 months ago (2 children)

I dont care about your purposes, I work in the sun day in, day out. I drink several litres of water and have to go into a hotbox of a portaloo to take a piss. Its like a shit and blue liquid scented sauna and I hate it.

[–] mrbubblesort@kbin.social 5 points 11 months ago (1 children)

That seems more like a workplace problem than a biological one

[–] ivanafterall@kbin.social 4 points 11 months ago* (last edited 11 months ago)

Are you going to tell me how to graft a second urethra down my leg or should I just Google it?

[–] Aussiemandeus@aussie.zone 2 points 11 months ago

Man have i got the solution for you. We call it dehydration.

So the trick is don't drink water get hot as fuck maybe pee once or twice all day.

And as a bonus knock off beers get you hammered

[–] HeyThisIsntTheYMCA@lemmy.world 7 points 11 months ago

No he's asking what if humans had cloacas

[–] Thurkeau@lemmy.world 1 points 11 months ago (1 children)

I can totally see that, though what if the body was able to adapt to the new configuration and keep the gut bacteria in its place, but the urine still flowed into the bowels for reprocessing? What else would the large intestines pick up aside from water and maybe salt?

[–] Rin@lemm.ee 2 points 11 months ago (1 children)

There's not much in urine except water, maybe a little bit of sugar if you're diabetic. I don't think this would be a beneficial adaptation. I'm pretty sure that if this was advantageous, it would have been adapted way earlier in our evolution.

[–] Delphia@lemmy.world -3 points 11 months ago (1 children)

Also girls should pee after sex to flush out the pipes. I can imagine that the works might get clogged up if dudes didnt pee out of the same tube they ejaculate out of.

[–] Shou@lemmy.world 1 points 11 months ago

Not a problem for men to worry about. It is however true for rats. They can get penis plugs because their sperm acts like glue.

[–] Rivalarrival@lemmy.today 24 points 11 months ago* (last edited 11 months ago) (1 children)

Consider, for a second, what would happen if and when the pressure in the colon exceeded the pressure in the bladder, and a urethra connected the two: fluid in the colon would backfeed into the urinary tract. The kidneys would ultimately be exposed to intestinal flora.

The prevalence of UTIs even with the "air gap" of separate waste streams tells me that this would be an extraordinarily bad idea, at least with our current biology.

If we had evolved in a more arid environment, there might be some advantage, but if we had, we would have a significantly different system to maintain homeostasis: it would have to be significantly more resilient to bacterial contamination than our current system.

[–] Chetzemoka@startrek.website 15 points 11 months ago* (last edited 11 months ago)

Can confirm, there is a condition that removes the air gap causing a pretty much continuous UTI. (Colovesical fistula: https://www.medicalnewstoday.com/articles/colovesical-fistula#treatment-and-management)

[–] LackingC10H12N2O@lemmy.world 21 points 11 months ago* (last edited 11 months ago) (1 children)

I have Crohn's disease and therefore already pee out of my a$$ on a regular basis.

0/10 would not recommend.

(obv. not exactly what OP is asking but i imagine it feels the same)

[–] elementalguy2@lemmy.sdf.org 7 points 11 months ago

Ditto. I had my large intestine removed and now adding even more liquid would not be pleasant.

[–] redcalcium@lemmy.institute 18 points 11 months ago (1 children)

Then you'll basically have a cloaca, and perhaps you'll ended up like bird and reptile which can't seem to hold their shit and also have watery shit. One of the great things about mammals is they're able to hold their (relatively) dry shit until they found a safe place to dump it.

[–] Catoblepas@lemmy.blahaj.zone 2 points 11 months ago

That might be a trainability issue rather than a physical capability issue, the more intelligent parrot species are able to be trained to defecate either on command or in specific spots.

[–] Drewdp@lemmy.world 13 points 11 months ago (1 children)

The kidneys already recover water and salt. Google the loop of Henley.

What we pee is what our body considers in excess. We intake a lot of our water from food, so we need a way to expel that. Peeing is much nicer than bloating and constant Diarra.

[–] Thurkeau@lemmy.world 0 points 11 months ago (2 children)

True, though as is, we still need to take in water due to a shortfall in what we do take in. That said, I'm also wondering if my proposal would also result in other waste products being recirculated and building up in the system, causing their own complications.

[–] Zeth0s@lemmy.world 8 points 11 months ago* (last edited 11 months ago)

You are asking for kidney stones. There's a chemical reason you want plenty of water to dilute your waste, that is avoid precipitation

Edit https://en.m.wikipedia.org/wiki/Precipitation_(chemistry)

[–] match@pawb.social 1 points 11 months ago

One waste product building up would be water, in that case

[–] _haha_oh_wow_@sh.itjust.works 12 points 11 months ago

Well, then urine trouble because that would be like having liquid poo all the time. Gross.

[–] BananaTrifleViolin@kbin.social 11 points 11 months ago

So the way evolution works, the design we have works well enough that it doesn't cause problems. It might be the best possible design or it might not, all that mattered is that whenever it arose in evolutionary history it was either an advantage over what camebefore in terms of survival so propagated or it was not detrimental and paired with something else genetically that propagated.

We can't definitively answer your question but we can speculate on why it's a good idea to separate urine and faecal matter. Urine is a reasonable medium for growing bacteria. That wouldn't matter in the colon but would matter if bacteria from the colon could ascend into the kidneys and diarupt it's function. Valves could help or a bladder that drains into the colon, but complete separation may just be better.

It may also be that the acidic nature of urine would disrupt the helpful bacteria we rely on to colonise our guts to help digest foods.

Another possibility is the constant flow of urine would mean our faecal matter would never dry out. It'd be like having diarrhoea all the time and we'd need to poop constantly. The colon retrieves enough water - but not all water - that's why poop isn't hard as rock. If it was flooded with fluid it may not need to retrieve fluid.

The fluid might even be stuck in a cycle between the colon and the kidneys and make it harder for the body to keep homeostasis - as the kidneys excrete more fluid to try and regulate fluid volume the the colon could just resorb it. Basically the colon could end up working against the kidneys and cause even more work for thenl body. It may just be less efficient than discarding water as needed.

Drier faecal matter in the colon and a reservoir of fluid in the bladder does also give us freedom to release when it is safe to do so, which may protect us from predators (having to stop to poop even a few times a day is dangerous compared to only going when you know it's safe to as there are more opportunities to be attacked by a predator). It would also be very easy to track an animal that leaves a constant trail of poop and urine uncontrollably behind it.

All or none of these may be reasons why we have separate urinary and alimentary tracts; it's impossible to know and would always be speculation. But regardless these do seem like reasonable reasons why we may have separate tracts.

[–] jaanus20@lemm.ee 4 points 11 months ago (1 children)

Not a biologist, just a normal dude. Isn't one function of urine to flush out toxins? With them staying in the intestines could it poison the human?

[–] Thurkeau@lemmy.world 2 points 11 months ago (1 children)

That's actually part of my question. The bowels also dump toxins overboard as well, but will they be enough to do the job?

[–] aubertlone@lemmy.world 2 points 11 months ago

I think you need to perhaps watch some videos explaining the anatomy/physiology of the gastrointestinal tract and urinary tract.

The kind of questions you're asking can be easily answered with an understanding of the systems I've stated above.

[–] rufus@discuss.tchncs.de 2 points 11 months ago (1 children)
[–] Thurkeau@lemmy.world 1 points 11 months ago (1 children)

A cloaca still has facilities for urine to be dumped overboard, doesn't it? My proposal is to recirculate it before dumping it overboard dry.

[–] rufus@discuss.tchncs.de 1 points 11 months ago* (last edited 11 months ago)

And what would you do with the water you've taken out in the drying process? Have seperate organs to seperate it (kidneys, colon) and a seperate set of organs to dump it out (pee)? That's returning to the way we humans handle it. Or you need to stop flushing things with the water and stop eating food that contains it. Or your organism just accumulates water and explodes like a water balloon if it has no way to get out. It has to go somewhere if you ingest it.

[–] sagrotan@lemmy.world 1 points 11 months ago

The beargryllneys?

[–] I_Clean_Here@lemmy.world 1 points 11 months ago (1 children)

What if my mother had wheels?

[–] Thurkeau@lemmy.world 6 points 11 months ago

I think that's called a bicycle.

[–] angrystego@lemmy.world 1 points 11 months ago (1 children)

The other solution would be to evolve a bladder capable of reabsorbing water.

[–] Thurkeau@lemmy.world 1 points 10 months ago

That is also something that I have wondered about, but that probably isn't a thing because of salt buildup.