this post was submitted on 24 Sep 2024
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How about we play, "Never have I ever"? (fedia.io)
submitted 1 month ago by bizarroland@fedia.io to c/asklemmy@lemmy.ml
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[–] deranger@sh.itjust.works 2 points 1 month ago

With alcohol it's very clear that there's one organ doing the heavy lifting

It’s not your liver, it’s your GABA receptors downregulating that gives you a tolerance. Your liver helps with the duration and hangover but the lower peak intoxication is mediated by the receptors. Likewise with cannabis, your THC receptors downregulate to give you a weed tolerance. It is also processed by the liver.