this post was submitted on 03 Aug 2023
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[–] autotldr@lemmings.world 24 points 1 year ago

This is the best summary I could come up with:


A "cancer-killing pill" has appeared to "annihilate" solid tumours in early research - leaving healthy cells unaffected.

Professor Linda Malkas, who has been developing the drug, explained: "PCNA is like a major airline terminal hub containing multiple plane gates.

"Our cancer-killing pill is like a snowstorm that closes a key airline hub, shutting down all flights in and out only in planes carrying cancer cells."

While initial results are promising, the research so far has only concluded that AOH1996 can suppress tumour growth in cell and animal models - with the first phase of a clinical trial in humans now under way.

The pill has been shown to be effective in treating cells derived from breast, prostate, brain, ovarian, cervical, skin and lung cancers.

PCNA had previously been labelled as "undruggable" - and it is hoped the breakthrough could lead to more personalised, targeted medicines for cancer in the future.


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[–] wheresmypillow@lemmy.one 16 points 1 year ago (4 children)

Looks like a treatment, not a cure, that will require ongoing supplies of medication. This is a pharma wet dream. We can’t cure your cancer, but we can keep it from growing for just $2000 per pill that cost us $1 to make.

[–] Neuraxis@lemmy.world 20 points 1 year ago* (last edited 1 year ago) (1 children)

Do you really think that pill cost 1$? A single approved therapy takes years to develop and over a billion dollars. But hey if you're view of an entire industry is shaped through Facebook comments I don't blame you.

Further, maintenance therapy already exists in many cancers. This is not a new concept for literally anyone in the field of medicine.

[–] wheresmypillow@lemmy.one 7 points 1 year ago (1 children)

No I don’t think it will cost a dollar. That was hyperbole.

[–] Black_Gulaman@lemmy.dbzer0.com -2 points 1 year ago* (last edited 1 year ago) (2 children)

That's what it is, a subscription based cure.

"as long as you buy our medicine you will live!"

I sure hope it isn't like this. Medicine just enough to stave the progress of the illness but also not enough to cure it.

[–] Carighan@lemmy.world 2 points 1 year ago (1 children)

I find it a bit reductive to call palliative care a moneymaking scheme overall. Especially cruel to workers in the field, which is one of the toughest one as far as mental health goes.

[–] Black_Gulaman@lemmy.dbzer0.com 1 points 1 year ago* (last edited 1 year ago)

Yeah I do understand what you are saying. And I may have gone too overboard with my pessimism. This being cancer and all.

It's just that too many bad actors have taken advantage of regular folks and their situations. It's hard not to react in a pessimistic view when there's hardly any good news to come by, or any good development that gets twisted into a nightmare of a tool just to take advantage of people's hope for better care.

[–] tastysnacks@programming.dev 0 points 1 year ago

I know what you're saying, but cancer being a chronic condition is great.

[–] yA3xAKQMbq@lemm.ee 10 points 1 year ago

At the moment, it doesn’t look like anything, since it’s just now in phase 1 trials, so nobody knows.

But if it does what it says, then yes, it might actually be part of a cure.

And I don’t know if you’re aware of it, as of now we don’t have a cure for cancer: https://xkcd.com/931/

You can look up the average treatment cost today, it’s something like $150000, good for your that you already know the price of this pill and that it’s big pharma‘s wet dream.

[–] atzanteol@sh.itjust.works 8 points 1 year ago

"Why don't they just cure cancer!"

🙄

[–] w00tabaga@lemm.ee 9 points 1 year ago

Heard about this on the radio yesterday, and looked into it further as we hear about “cancer curing pills” all the time and they usually are nothing. This one does seem to have traction however IF it can make it through human trials. So obviously could mean nothing if it doesn’t pass this phase, and it will be there a long time, but this is very promising news.

[–] xc2215x@lemmy.world 7 points 1 year ago

Good to see this pill be created. Very nice.

[–] XpeeN@sopuli.xyz 1 points 1 year ago (1 children)
[–] autotldr@lemmings.world 2 points 1 year ago

I just created the summary! You can find it at https://lemmings.world/comment/894209. (I tried to create the link for your instance but I failed miserably, for which I'm very sorry).

[–] Fedizen@lemmy.world -1 points 1 year ago (1 children)

Joe Brandon filling his campaign promise /s

But it is good to see more treatment options

[–] Burn_The_Right@lemmy.world 4 points 1 year ago* (last edited 1 year ago)

Maybe conservatives will treat this medical advancement the same as other medical advancements. To be fair, these pills are obviously loaded with 5G tracking chips and are obviously not as effective against cancer as horse dewormer or bleach.