I would recommend GrapheneOS. There are literally no Google dependencies at all. They have reimplemented privacy friendly alternatives for all built in functionalities typically depending on google such as for location.
Additionally, with their custom built compatibility layer, they allow you to install google play services as a regular app, and fully control which permissions you grant it, which can be useful for apps which depend on google to give you notifications.
Grapheneos is also at the bleeding edge of speed to deliver security updates several times a week.
And with user profiles you can fully separate apps yet they have a custom way of piping notifications between profiles as profiles is a particularly convenient way to isolate apps and prevent them from knowing what other apps are installed.
It's not perfect but it's definitely the most secure and most privacy respecting, it's user friendly, puts the user back in control and works really well the moment you have adjusted to the new way of using android and make use of all the features.