this post was submitted on 15 Oct 2024
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It's more complicated than that and I think it's just not worth the risk. I have a nerve disorder which I take the medication for, and it's three medications: an SNRI, a GABA analogue and an anticonvulsant. I just don't know that adding LSD into a mix like that is a good idea, because even if none of those individually could cause it, collectively, who knows? It's not like it's a common mix.
But I do appreciate it.
As a former recreational user of many substances(not LSD though), I understand your hesitancy. I had many great experiences on shrooms so I tend to recommend that before LSD. I just think it's not as intense and has a lower probability of negative interactions or experiences, but that's just based on what I've seen/heard/read. There are knock off versions of shrooms in vape shops but I have no idea what they are like.
It's very much a different strokes for different folks kinda thing. People I know prefer LSD and other, closely related lysergamides because it gives a bit more of an energy boost - I've heard it described as shrooms with a shot of espresso. Others prefer shrooms because it's a little more laid back feeling.
Granted, your set and setting is really going to set the tone for whatever psych you ingest. Things can go amazingly or very, very badly with either substance depending on your headspace and how you set yourself up/structure your environment for the experience.
I appreciate it. I've done shrooms before I got on this medication, so I do know what that's like. I just am not going to take any chances these days.
I won't pretend to have such deep knowledge as to claim to know they're safe, but as far as I'm aware (which again, is some, but am not a medical professional), the N of the SNRI shouldn't really be affected directly. But that doesn't mean that if you get a little bit jittery when you're going up that you won't have increased norepinephrine which would then be blocked from reuptake.
So yeah, it's somewhat more complicated. Anticonvulsants are basically what you'd use to come down from a trip (depending on which type, there's a lot), so I don't see any obvious risks in that either. GABA should likewise not be a problem, as not directly affected, and like anticonvulsants, some of them are used as anti-psychotics.
However with those meds, even if I could say it's safe (whichever again, I can't, but personally believe it to be of low risk, due to the things I've read concerning), I don't know if I'd say it's worth it, really.
Like you wouldn't enjoy a night out if you had the flu, basically, but it wouldn't be that risky. Even though like getting a bad case of pneumonia and not treating it might be fatal, but quite a small risk. Probably on the same level, these risks.
No-one, honestly. But the internet is pretty hard at work on it.
Although they started with recreational polysubstance combinations, actual meds don't appear on the list too often unless they can be uses recreationally.
https://en.m.wikipedia.org/wiki/List_of_polysubstance_combinations
But yeah, safety is #1 when using drugs.