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glycine. so if anyone is aware of cron there was a study which showd methionine restriction seemed to have a similar effect and a further study that glycine which helps eliminate glycine to do so as well as a supplement. Mouse studies though (not cron which has more data but the others are like one study each last I saw.)
Cron?
calorie restriction with optimal nutrition. walford used it when an emergency happened in biosphere and its been done up to monkey levels so its pretty well studied. He was following it himself but died to a genetic disease.