this post was submitted on 22 Mar 2024
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U.K. cracks down on synthetic opioid 10 times stronger than fentanyl causing overdoses in Europe (www.cbsnews.com)
submitted 8 months ago by throws_lemy@lemmy.nz to c/europe@feddit.de
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[โ€“] sqgl@beehaw.org 3 points 7 months ago* (last edited 7 months ago) (1 children)

What does it mean for drug B to be X times stronger than drug A? Is it per milligram? Per LD50?

[โ€“] pedroapero@lemmy.ml 2 points 7 months ago (1 children)

That would be the required dosage to get a regular hit (or to feel something maybe)

[โ€“] sqgl@beehaw.org 2 points 7 months ago* (last edited 7 months ago) (2 children)

Measured by weight (mg)?

[โ€“] tryptaminev@feddit.de 4 points 7 months ago

https://en.wikipedia.org/wiki/List_of_benzimidazole_opioids

There is the Analgetic Potency listed, which would be the weight factor. However looking at the individual compounds the numbers can vary drastically, i didnt find any LD50 information and many of them being just completely new.

For reference Heroin has a potency of about 2 compared to Morphine and Fentanyl has a potency of about 100.

So this is uncharted territory both in terms of potency and the compounds themselves. There exists no knowledge about the precise effects, about side effects, long term harm, addiction...