godzillabacter

joined 1 year ago
[–] godzillabacter@lemmy.world 3 points 3 days ago (1 children)

The Sly Cooper Trilogy +/- Thieves in Time

[–] godzillabacter@lemmy.world 8 points 1 month ago

This is incorrect. You just can't switch manufacturers easily if you're stable on one. But that's not a brand vs generic thing, that's an any manufacturer to any-other manufacturer thing. Same with warfarin, narrow-therapeutic index antiepileptics, etc.

[–] godzillabacter@lemmy.world 4 points 2 months ago (1 children)

No idea unfortunately, but definitely not to release pressure. You don't get air in your brain, it's all fluid. Outside of the hospital, all the drains drain to somewhere internal, usually the abdominal cavity

[–] godzillabacter@lemmy.world 46 points 2 months ago

Am doctor. Outside of very rare and specific causes of headache, no this wouldn't fix anything, just put you at risk for infections.

[–] godzillabacter@lemmy.world 22 points 2 months ago (5 children)

Am a doctor, this wasn't actually a migraine and is not how migraines happen. Shunts are placed for elevated intracranial pressure, which can occur for a number of reasons, and do cause headaches. But it's a very uncommon cause of headaches and a shunt will not fix your actual migraines or tension headaches.

[–] godzillabacter@lemmy.world 7 points 2 months ago (1 children)

Cellular insulin resistance is the definition of Type II diabetes

[–] godzillabacter@lemmy.world 8 points 8 months ago

Statistically? Cancer or heart disease.

[–] godzillabacter@lemmy.world 9 points 8 months ago

It's not that we don't use mode, there are definitely times mode is used. It's just that mean (and median as well) contain a lot more useful information about distributions that we often care about. For a normal distribution mean, median, and mode should all be identical. So why do we use mean? Because mathematically, the mean is what underpins the formula for the normal distribution, not median or mode, and when you're talking about doing math with normal distributions mean is the thing to talk about (along with standard deviation).

We use median a lot too, you probably just don't hear it called median very often. The median is useful in non-normal distributions, and it defines the 50th percentile, so along with the 25%-ile and 75%-ile you've got your quartile distributions. We use these all the time to talk about grades in schools, or when we talk about home prices distributions in a given area, or salaries within a given field.

We use mode too, again just by a different name most of the time. Any time you've asked "what's the most common blank" you're basically asking for a mode. When we talk about "average" income in a country, we're usually actually talking about median or mode. Favorite animal? Answered as a mode.

You have to use the right statistical tool for your question: unfortunately English doesn't do a good job of conveying this without math jargon.

[–] godzillabacter@lemmy.world 3 points 8 months ago (1 children)

I'm sorry you're getting downvotes. I'm betting the bulk are because you're in c/askscience saying you don't have any evidence to support your question, but that's kinda the whole reason to ask a question. You weren't speculating in a top level comment so I think it's rude to be downvoting. As far as I can tell you're asking genuine questions which is kinda the whole point of this community. Fuck the haters, ask questions when you're curious!

[–] godzillabacter@lemmy.world 2 points 8 months ago

It's awesome that you're already setting some stuff up. Feel free to DM me if you've got any questions!

[–] godzillabacter@lemmy.world 2 points 9 months ago (2 children)

I'm putting in my rank list for EM right now. Some people certainly have some...peculiar...ideas about health and healthcare.

[–] godzillabacter@lemmy.world 11 points 9 months ago (3 children)

But most animals don't leave it intact. They chew through it shortly after birth. You can't really have a tissue that is sturdy enough to survive tension during fetal development and vaginal delivery that then instantly falls apart, so it has to be manually severed after delivery. The vast majority of mammals don't let it stay attached for long at all, because their offspring are pretty mobile immediately after birth. From my reading of some of the random websites that recommend this, apparently it was based on the observations of a single species of higher ape (a chimp I think) that doesn't sever the umbilical cord quickly. But when we have been severing cords as a species for generations and the vast majority of other mammals sever the cord with their teeth, I think the evolutionary biology evidence points towards severing the cord quickly.

Now evolutionary biology isn't a solid basis for medical practice, but we don't really have much scientific data at all to base this on at this point. There have been reports of increased rates of serious infections from the practice, which has face validity with the fact that you're leaving a devascularized piece of tissue attached to the vascular system of neonate with an immature immune system. Outside of infection, there has been some case reports of polycythemia (excessively high red blood cell count) and jaundice in these infants. This makes sense physiologically. While attached to the placenta there is a greater intravascular volume available to the infant, which is the entire basis behind delayed cord cutting. It stands to reason that continuing to allow that extra blood volume to enter the infant would result in polycythemia and jaundice.

I'm not intimately familiar with the foundational literature by which the standard DCC cutoffs of 1 minutes or cessation of umbilical pulsatility were founded upon. There could be a very real argument for saying, should the time be 2 minutes? 5 minutes instead of 1? Or should we at least study it if it hasn't been already?

In summary, we have a piece of dead/dying tissue attached to a physiologically stressed neonate with an immature immune system. Leaving it attached for days is in contradiction to the vast majority of other mammalian labor behaviors, is inconsistent with the majority of human's labor history, and has a clear pathological mechanism by which the commonly reported complications can be easily explained. Without some legitimate evidence to actually support benefits or disprove the risks, I think this practice should be discouraged by healthcare professionals.

 

I've been a DM for about 3 years, and have predominantly run one-shots and short campaigns in DnD5e and PF2e. I have a player who persistently builds primary caster based characters, but then won't do anything in combat but "I stab it with my dagger." They rarely use cantrips, and basically won't cast a leveled spell unless I suggest it immediately before their turn. They seem to enjoy playing despite the fact that they're far too squishy to be a front-line melee character and don't utilize most of their class features. I've talked with them explicitly about how their play style seems to be discordant with the kind of play they want to do, and that maybe next time they should try a paladin/champion or a fighter/rougue subclass with some minor casting. They agreed at the time that sounded like a good idea, but low and behold showed up to the next one-shot with a primary caster, and over 3 hours of play and 3 combats never cast a single spell, including a cantrip.

I enjoy playing with this persons as a whole. They are engaged in the fiction, and are particularly engaged during exploration activities. They tell me they also find combat quite fun, and they are requesting I run a mega dungeon in the near future.

As a general rule, I like to let people play how they have the most fun, but issues have arisen with this play style. Namely, all of my TPKs have been associated with this player charging a squishy character directly up to a significantly stronger villain and continuing to stab it with a dagger until they went down, significantly hindering the party in the action economy and resulting in a TPK. I feel I have to intentionally weaken all of my encounters to keep the party feasible in the face of such mechanically poor combat choices.

What else can I do to help drive this individual towards melee builds, and/or help encourage them to change their play style to better suite the caster classes they choose?

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