It's a good way to get prion disease for sure.
this post was submitted on 22 Oct 2023
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...Would the prions make you high? π€
Can you taste memories
well they would certainly destroy your brain
Are those the ones that give "laughing disease" or whatever it's called - that's in fact very deadly
Why would that be likely? Wouldn't that only be the case of the brain you are eating already has it?
For whatever reason prion disease has a chance to spontaneously occur when mammals cannibalize. Especially if they are obligate herbivores. Prion disease was originally discovered in cows transmitting it to humans due to some particularly sick fuck running a slaughter factory thinking it would be a good idea to put cow meat scraps back in their feed soylent green style.
Not sure about that but it is a great way to get Kuru
Often takes years or even decades for symptoms to appear after exposure
Oh jolly, everything about this resembles the Mad Cow Disease
[...]
The epidemic likely started when a villager developed sporadic CreutzfeldtβJakob disease and died. When villagers ate the brain, they contracted the disease and then spread it to other villagers who ate their infected brains.
Jolly
It's a prion disease. Mad Cow, Creutzfeldt-Jacob, Chronic Wasting (so far only seen in deer), and Scrapies (known of for a long time and so far limited to sheep and goats) all start with a misfolded protein and gradually break down the brain till it looks like a sponge.
Specifically a spongiform encephalopathy. Completely incurable and universally fatal. If you contract a prion disease medical science can only ever prolong the inevitable, and it is extremely unlikely that will ever change barring some unknown hyper futuristic nano-machine technology.
And Chronic Wasting Disease (CWD) in cervids such as deer, moose, and elk, which thankfully has not been shown to be transmissible to humans yet. Prions are the stuff of nightmares.
Oh, and Fatal Familial Insomnia.
It resembles mad cow disease because they're both prion diseases, which are more or less only spread by consumption of brain.
Some of the other nasty ones that keep my a little freaked out are Chronic wasting disease, aka the zombie deer disease and Fatal Insomnia , which just sounds like something straight from a horror film.
β¦. Just why would they do that tho?
As part of mourning people would eat parts of dead family members
This is actually not good stats. In the general population, the current situation with prions is that they are extremely rare. But that's for the general population. If you are around brain eaters then your risk for exposure is exponentially higher. For example, the odds that a person from the general population is exposed to HIV is relatively low. But if you instead only focus on people that live in smack houses in an abandoned part of detroit, then those people have much different odds.
The problem with prions is literally fucking everything though. There is a reason they will wipe out thousands of cows if they find out even one has prion disease. First is time. They usually do not show symptoms for a long long time. Next, is prions are damned near impossible to get rid of. So you're hanging out with brain eaters, but you aren't eating brains? But did you use their forks? Because the dishwasher isn't getting rid of that prion. Goddamn medical autoclaves do not get rid of them. I know someone that was participating in a neurosurgery, and after a couple days after the surgery, they found out the patient had a prion disease (probably CreutzfeldtβJakob but I don't recall for sure). Well that caused havoc because of possible exposure and the lag time between the surgery and finding out. They destroyed a lot of things, had intense decontamination for others, had to inform some people in the hospital about possible exposure. Even with the low risk, just imagine being one of those people. For the next 20 years, the thought is probably just lingering in the corner of their brain that a dumbass protein that couldn't follow directions and decided to make its own rules is also lingering around a corner of their brain.
But yeah, cannibalism in general tends to lead to increased rates of disease and new diseases. Which is logical. Most diseases aren't interspecies, but if you are eating the same species then you can catch anything that has lingered. Parasites, bacteria if you like your human flesh medium rare, viruses, and prions. So I highly suggest against hanging out with cannibals.
Holy shit the neurosurgey one is horrifying.
Yup. Most hospitals have a one-and-done policy for instruments used in brain surgery now.
Maybe the dead guy was rich
To get high
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Did anyone else learn about Kuru from the Book of Eli movie?
For me, it was the game Dead Island
That wikipedia article reads like an a try in the sco wiki.
Nah, it's the other way around, you'd have to be really fucking high to wanna eat human brains
Zombies really just hit some of that snoop dogg good good.
Like... Bath salts high.
no your stomach acid would denature most of the proteins, then they'd be conjugated at the liver so whatever goes in will be transformed by what comes out. A lot of those hormones are tightly regulated so I'm thinking even if they make it into circulation they'd be eliminated fairly quickly. Only exception would be if they're acid stable, not impacted on their way through the gut/metabolised by microbiota, absorbed in tact and still active after the first pass effect. Also theres enzymes like trypsin in your stomach that are specifically for degrading proteins so I doubt it would make you anything other than a canibal.
Would smoking raw human brains make you high?
Wait no thermal degredation
Would nebulizing raw human brains make you high? Especially of I got a little brain-diffuser in the corner that just filled the room with the aroma
Get me some brains and I'll let you know.
Okay, hear me out. Rectal route?
Boofing brain
...And I'm done. No beating this today.
Coward. I'll beat to this.
Boofing 2: Brain Boogaloo
It would still go through the liver for metabolism. The only thing "boofing" effectively does is skip the stomach part of the digestive process. To take up anything from the digestive tract, it gets transported through the intestinal lumen and into the mesenteric and hepatic portal system. The liver filters everything that gets into the blood from the gut before it goes into the inferior vena cava and into the rest of the circulatory system.
Correction to clarify: the lower gut/colon mostly only takes up water and certain vitamins that are released by gut bacteria, and very small molecules like ethanol can sometimes get through as well. The very lowest part of the colon does have a vascular supply that can bypass the liver, and there are some medications designed to take advantage of the select receptors and transporters down there. However, neurotransmitters and peptide hormones (which is what OP was asking about) would likely not get taken up until it was much higher up in the digestive tract, and at that point it would go through the hepatic portal system.
Thank you to those that corrected me. Intestines are actually fairly complicated.
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you're mostly right, however trypsin is produced in the pancreas and excreted into the duodenum, so not in the stomach. I think maybe you're thinking of pepsin?
Ya it was the first one to pop into my head as an example, the main point is anything active would be neutralized one way or another by the time it ended up in circulation.
yeah i agree.
conjugated???
The liver "conjugates"/metabolises a bunch of stuff, its been almost a decade since I studied this stuff but bassically it will remove or add functional groups on/off a given compound. Most of what you eat heads straight to the liver for "processing" where food (and orally administered drugs) get altered prior to circulation. Its part of the first pass effect.
...so how many brains would i have to inject to get high?
Simplifying the question a bit:
-
Which hormones can be absorbed when eaten, and what effects would you feel
-
At what concentration are those found in the brain
Having absolutely no formal knowledge, I doubt it. The brain afaik is mostly fat..We also evolved eating animals we hunted and we didn't just eat the meat. We ate the organs, liver, brain, etc. The liver is really full of that stuff and doesn't make us high.
Yeah. Cows are way bigger than us. If we got high eating brains we would know from eating animal brains.
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Question OP, were you high when you thought about this?
Shamefully, no. I was pondering my melatonin fruit gummies after lots of coffee, though. Coffee tends to get me a bit high sometimes. (I hadn't eaten any gummies after the coffee, I was just thinking about them.)
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That's how you become a Wendigo.
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