The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
Well for starters, your instance users are pretty much the only ones popping in and complaining that we're defederated from lemmygrad, despite it not affecting you at all.
Y'know, since you're on a different instance and all.
Attempting to exert influence on a different instance seems kinda like the federation attempting to affect this instance, no?