this post was submitted on 13 Sep 2023
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Very interesting. I wonder what their metric was for determining it doesn’t work. Anecdotally, I use phenylephrine HCl alone and find it keeps me clear most of the time, but not always. I also have to be well hydrated or it actually makes me even more stuffed. Maybe the inconsistency is why they reached this verdict? Maybe I’ve just been experiencing a placebo effect?
The metric was that it is no more effective than placebo. It is a very old drug and was grandfathered in from a time before modern standards.
The FDA was told this by researchers in 2007, but they wanted mOrE dAtA.
Edit to add: It does have more effectiveness when used nasally as opposed to orally.