Can you give some more info? PC or console? Windows or Linux? Mods or no mods? Did you verify game files? Fresh install or after the update? HDD or SSD? Is HDD mode on?
Cyberpunk 2077
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PC , Windows 10, on external SSD, few mods but none installed recently and no big changes through them. Version 2.01, pirated for now.
I can't know for sure but the most likely culprits are the fact that the ssd is external or a mod acting up. You could try backing up your save files, reinstalling the game without mods, and putting them back to see if you can make new saves.
I just realised that another program was filling up my C: drive and making some space seems to have helped so let's hope it was just too little space for the save files.
That should be easy to test, good luck!
You should ask on the steam forum.
I would but they're all busy complaining about the latest update