So I guess you want to get more mature recommendations?
To your eternity - very beautiful, but not finished yet
Ghost in the Shell - a must watch
Samurai Champloo - very fun
Texhnolyze - just watch 1 or 2 eps, if it is for you
Serial experiments Lain - not about adults but confusing and more Seinen I'd say
Hellsing Ultimate - gory vampire hunter series that also is a bit silly
And of course the Ghibli movies are highly recommended