this post was submitted on 22 Jul 2023
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Computer chip with built-in human brain tissue gets military funding::undefined

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[โ€“] andrewrgross@slrpnk.net 73 points 1 year ago* (last edited 1 year ago) (16 children)

Having worked in neuroscience and synthetic biology I want to give some context.

First, here is the actual paper: https://www.cell.com/neuron/fulltext/S0896-6273(22)00806-6

Second: is this bullshit?

Overall, I think this research was well-conducted and meaningful, although use of the words "intelligence" and "sentience" are deliberately sensationalist. In the context of the paper, they mean that it is responsive to its environment in the same way a sea sponge or Tomagotchi is.

The cells are neurons cultivated from dissolved rat brains (after they were gently euthenized) and reprogrammed forebrain neurons cultured from cells collected from a baby's foreskin after circumcision (which isn't unusual even though it's weird if you don't work in this field).

Then, the cells were transferred to a commercially available plate with thousands of little electrodes on it that can read the random electrical pulses healthy neurons in a dish routinely shoot off, and also stimulate these. The team then used a program to take the input value from a bunch of the readings and map one area of the plate's activity to moving the paddle up and one section to down, and then had another region that was given stimulation of random noise except when the ball hit the paddle. Then they tried to quantify if this loop incentivized the neurons to coordinate to try to increase the number of ball strikes. I don't know if it could read the ball position or just got a "reward" when it collided.

Really, they expanded an existing set of tools elegantly in a way that can improve our ability to study neurons in a dish. Which is great. Culturing neurons well is harder than people like to admit. BUT: nothing about this currently advances computer science in a specific way. It might in ten years, but so might superconductors. There's nothing about a biological network that is inherently superior to other informational networks, except that they're currently the underlying component of the most successful informational networks we know of. And, of course that they get you hot, hot, HOT press, which is certainly nice when you're trying to get money to do research.

[โ€“] asphaltkooky@lemmy.world 4 points 1 year ago

Foreskin: the essential component of all scientific advancements.

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