When I'm lazy I throw everything in there. I mostly try to save ancestral legendary because sacred and normal legendaries are just kinda useless at this point.
EXCEPT when they have good rolls. Check the rolls on the items. If they are good rolls then save them, or extract the aspect. You might need it in a future build.
I also try to save ancestral rares that seem interesting.
At this point gems I couldn't care less. I don't every bother picking them up.